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Anti-Micobacterial Properties of Mangosteen

You are probably familiar with antibacterial products, such as antibacterial soap, designed to kill bacteria. You may be less familiar with antimycobacterial medications. Antimycobacterial drugs are designed to treat mycobacteria infections. Mycobacteria are still bacteria, but they are not killed with simple anti-bacterial compounds. Instead, antimycobacterial drugs target specific strains like tuberculosis and leprostatic agents. As you know tuberculosis and leprosy were two diseases no one could cure or stop. Today, these antimycobacterial drugs at least help alleviate symptoms and ensure a person can live longer if infected with mycobacteria. Despite the inability to cure the disease, the treatment for both has been around in some form since ancient cultures walked the earth

In Southeast Asia, Mangosteen fruit and its rind was used to treat various illnesses, although they may not have tried it on lepers or TB patients. One study has been conducted in the last few years, regarding three Xanthones formed from Mangosteen rind. These Xanthones were used to test the inhibitory properties of the Mangosteen compound to combat tuberculosis. The study was conducted at the Department of Chemistry in the Faculty of Science, at Srinakharinwirot University, Bangkok, Thailand.

The Xanthones were derived from the fruit hulls, edible fruit, and seeds of Mangosteen. The study examined the anituberculosis potential of Mangosteen. Using various concentrations and three Xanthones, the university published their results. Mangosteen-02 prenylated Xanthones: Alpha, Beta Mangostins, and Garcinone B were tested against the mycobacterial Tuberculosis strain. The results showed significant inhibitory qualities against tuberculosis when a minimum concentration of the three Xanthones was given. The concentrate was 6.25microg/ml.

The study is not completely conclusive. More testing will be necessary to determine the full inhibitory effects of the three Xanthones against tuberculosis and other mycobacterial strains. However, the results are promising that adding Mangosteen to your diet is a healthy way to avoid mycobacterial infections.

In the lab the entire fruit is used. The rind or peel is very tough and sour. It is difficult to eat on its own. There are Mangosteen juices being made that contain the entire fruit. It goes through a process to extract all the nutrients and Xanthones found in Mangosteen. In this way, you can drink 30mL of juice, frequently to help your immune system fight against mycobacterial infections.

You can think of inhibitory effects as trying to fit two puzzle pieces together. You know that one puzzle piece is designed to fit into another. Your cells are like this. Healthy cells have a receptor, which is supposed to attach to another cell. They should fit like a puzzle piece. However, when bacteria are introduced to these cells, the shape of the receptor can change. A product like Mangosteen juice is able to fit into the misshapen cell to stop the replication of the bacteria.

Although the science into Mangosteen is in its early stages, history shows us that it has healing properties, you do not want to miss out on. Even drinking the juice a couple times a month can help you become healthier.

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